Synthetic microbe lives with fewer than 500 genes

first_imgWhen it comes to genome size, a rare Japanese flower, called Paris japonica, is the current heavyweight champ, with 50 times more DNA than humans. At the other end of the scale, there’s now a new lightweight record-holder growing in petri dishes in California. This week in 
Science, researchers led by genome sequencing pioneer Craig Venter report engineering a bacterium to have the smallest genome—and the fewest genes—of any freely living organism, smaller than the flower’s by a factor of 282,000. Known as Syn 3.0, the new organism has a genome whittled down to the bare essentials needed to survive and reproduce, just 473 genes. “It’s a tour de force,” says George Church, a synthetic biologist at Harvard University.The microbe’s streamlined genetic structure excites evolutionary biologists and biotechnologists, who anticipate adding genes back to it one by one to study their effects. “It’s an important step to creating a living cell where the genome is fully 
defined,” says synthetic biologist Chris Voigt of the Massachusetts Institute of Technology in Cambridge. But Voigt and others note that this complete definition remains a ways off, because the function of 149 of Syn 3.0’s genes—roughly one-third—
remains unknown. Investigators’ first task is to probe the roles of those genes, which promise new insights into the basic biology of life.As Syn 3.0’s name suggests, it’s not the first synthetic life made by Venter, who heads the J. Craig Venter Institute (JCVI) and is a founder of Synthetic Genomics, a biotech company, both in San Diego, California. In 2010, Venter’s team reported that they had synthesized the sole chromosome of Mycoplasma mycoides—a bacterium with a relatively small genome—and transplanted it into a separate mycoplasma called M. capricolum, from which they had previously extracted the DNA. After several false starts, they showed that the synthetic microbe booted up and synthesized proteins normally made by M. mycoides rather than M. capricolum (Science, 21 May 2010, 
p. 958). Still, other than adding a bit of watermark DNA, the researchers left the genetic material in their initial synthetic organism, Syn 1.0, unchanged from 
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M. capricolum to see whether either would produce a viable organism.“The big news is we failed,” Venter says. “I was surprised.” Neither chromosome produced a living microbe. It’s clear, Venter says, that “our current knowledge of bio
logy is not sufficient to sit down and design a living organism and build it.” Venter and his colleagues had better success with trial and error. They divided Syn 1.0’s genome, with its 901 genes, into eight sections. To the beginning and end of each section they added identical DNA tags that made the pieces easy to reassemble. That allowed them to treat the sections as independent modules, removing each one in turn, deleting chunks of DNA, then reassembling the full genome and reinserting it into M. capricolum to see whether it produced a living cell. If the altered genome wasn’t viable, they knew they had cut out an essential gene that had to be restored. The researchers also assessed the necessity of numerous genes in the microbe by inserting foreign genetic material, called transposons, to disrupt their function.All this enabled them to systematically whittle away genes that either had nonessential functions or duplicated the function of another gene. In the end, Venter says, his team built, designed, and tested “multiple hundreds” of constructs before settling on Syn 3.0, with a genome about half the size of Syn 1.0’s. (Syn 2.0 was an intermediate stage in this process, the first microbe with a genome smaller than that of M. genitalium, which with 525 genes has the fewest of any free-living natural organism.)Once the whittling was complete, the researchers reordered the remaining genes, aligning ones that work in common pathways. The procedure tidied up the genome much as a computer compresses and re
organizes files on its hard drive to save disk space. This will likely make life much easier for synthetic biologists who will experiment with Syn 3.0 in the future, Voigt says.With a total of 531,000 bases, the new organism’s genome isn’t much smaller than that of M. genitalium, with 600,000 bases. But M. genitalium grows so slowly that a population of cells can take weeks to double. Syn 3.0, by contrast, has a doubling time of 3 hours, suggesting that it thrives with its slimmed down genome. “We’re not saying this is the ultimate minimum genome,” 
Venter says. For now, however, Syn 3.0 reigns as the world’s new lightweight champ.last_img read more

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UAAP Juniors: UST outlasts Adamson in 4th place playoff

first_imgCansino also contributed nine rebounds, six assists, and two blocks for UST, which will now brace for defending champion Far Eastern University-Diliman in the first level of the stepladder semis on Saturday.The victor of that knockout game will take on twice-to-beat National University.FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSPrivate companies step in to help SEA Games hostingSPORTSBoxers Pacquiao, Petecio torchbearers for SEA Games openingSweeping the elimination phase, Ateneo is now firmly in the championship series as it awaits its date in the best-of-three series.Kobe Palencia chipped in 15 markers, while Bismarck Lina tallied a double-double effort of 12 points and 12 boards for the Tiger Cubs. Joem Sabandal led the charge for Adamson with 20 points, nine rebounds and nine assists. Robredo: True leaders perform well despite having ‘uninspiring’ boss PLAY LIST 02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games MOST READ Sports Related Videospowered by AdSparcRead Next CJ Cansino did not want his run in the UAAP juniors basketball tournament to come to halt just yet as he saved University of Santo Tomas in overtime to beat Adamson, 73-72, in their fourth place playoff Wednesday at Blue Eagle Gym.The newly minted Season 80 MVP unloaded eight of his 24 points in the extra period, none bigger than his huge bucket with 1:13 mark left to give the Tiger Cubs a 73-68 lead before holding off a belated rally from the Baby Falcons.ADVERTISEMENT LATEST STORIES Do we want to be champions or GROs? – Sotto View comments PH military to look into China’s possible security threat to power grid Ethel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ Don’t miss out on the latest news and information. ‘We cannot afford to fail’ as SEA Games host – Duterte SEA Games: PH still winless in netball after loss to Thais ‘A complete lie:’ Drilon refutes ‘blabbermouth’ Salo’s claims Hotel says PH coach apologized for ‘kikiam for breakfast’ claim For the complete collegiate sports coverage including scores, schedules and stories, visit Inquirer Varsity. UAAP volleyball: Adamson trumps UP for 2nd straight win BeautyMNL open its first mall pop-up packed with freebies, discounts, and other exclusiveslast_img read more

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With Global Warming, Delay is Not An Option

first_imgWRI’s Debbie Boger responds to Bjorn Lomborg’s faulty global warming conclusions. NOTE: This story first appeared on The Huffington Post.After reading a transcript of Fareed Zakaria’s interview with Bjorn Lomborg on Global Public Square on CNN this past Sunday (June 15), my colleagues and I feel compelled to clarify several points which merit clarification as well as context.WRI has rebutted Bjorn Lomborg’s logic and conclusions about global warming before (see here), and we will do so again.Countless peer reviewed studies all indicate that the threat of climate change is real and that emissions of greenhouse gases from human activities will change the climate in catastrophic ways if unchecked. Because greenhouse gases remain in the atmosphere for many years, we do not possess the ability to fully avert climate change. However, we do have the ability to control our own destiny and avert the most serious consequences.Despite Mr. Lomborg’s fatalistic outlook on the problem, we must address global warming now, and there are good ethical and economic reasons to do so. In stark contrast to the idea that simply adapting to global warming will be cheaper than preventing it, Lord Nicholas Stern did a comprehensive economic assessment of the costs of climate change in the Report on the Economics of Climate Change. In his words, he found that:The overall costs and risks of climate change will be equivalent to losing at least 5% of global GDP each year, now and forever. If a wider range of risks and impacts is taken into account, the estimates of damage could rise to 20% of GDP or more. In contrast, the costs of action – reducing greenhouse gas emissions to avoid the worst impacts of climate change – can be limited to around 1% of global GDP each year.Lomborg’s assertion that it will be easier to adapt to climate changes than to reduce emissions also ignores much of the science. The real issue is not so much the gradual changes that will take place, including sea level rise, the disappearance of glaciers that provide many countries with reliable water supplies, and so on. Rather, it lies in the potential for much more dramatic change as the climate reaches certain “tipping points”. If the Greenland ice sheet were to melt, a threat that looks increasingly possible, sea level rise would be measured in meters, not centimeters. Cutting emissions today is not just about tweaking sea level rise as Lomborg suggests, but about insuring against unpredictable but potentially catastrophic effects. Acting now allows us to avoid taking even more aggressive measures later.The case for action is clear, and we are left to tackle the question of what is feasible and reasonable. Fortunately there are already a number of opportunities for greenhouse emissions reductions readily available, opportunities that can improve fuel diversity and security, and in the case of energy efficiency even save industry and consumers money. Furthermore, technologies like wind energy are highly evolved and already being deployed at high rates in many parts of the world. Mr Lomborg seems to see technology as something that turns up magically, but in fact it is climate policies that have been driving the innovation in many areas of energy technology. The German renewable energy support that Mr Lomborg derides does not merely postpone global warming for an hour: it creates the economies of scale that allow these technologies to be taken up around the world. Similar policies in his own country of Denmark have made his compatriots the world leaders in wind energy, and have underwritten the huge deployment of these technologies today in China, India and other countries. It is a fallacy to suggest that new technologies negate the argument for policy; they ARE the argument for policy. His reference to research and development as the means to reduce costs suggests a lack of awareness of where many of these technologies are today. It is not only R&D (though R&D is necessary), but deployment and economies of scale that are needed, and that are the main aims of climate policy. And solar will be competitive with fossil fuels long, long before “mid-century” thanks to these policies. To fully harness the creative minds of industry we must institute market-based programs that put a price on carbon and provide the regulatory certainty needed for private investment.Mr. Lomborg also implies that China and India will not be ready to deploy clean energy themselves until that far distant date when the costs are at rock-bottom. He should perhaps visit China, where wind energy is being deployed faster than anywhere else in the world and has built one of the world’s leading solar industries. China has identified climate change as a key threat to its economy, and clean energy as a centerpiece of its development.In closing, we believe that acting now to address climate change will not only (hopefully) avert catastrophic consequences, it will create jobs, improve energy security and improve people’s lives the world over. Let’s get started now.last_img read more

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Mysterious Death

first_imgaptn National NewsHealth Canada is investigating the death of a man in the Manto Sipi Cree Nation in Manitoba. The community is located about 600-kilometres northeast of Winnipeg. On Sunday evening, 27 year old Kirby Wood sought medical treatment at a Health Canada nursing station on the reserve.Less than 24 hours later Wood was dead.The organization that represents northern reserves says the death shows the poor state of health care in the north.There are now calls for an inquest to look into his death.last_img

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Moroccan-US Defense Advisory Committee Holds 9th Meeting

Rabat – Upon instructions of HM King Mohammed VI, Supreme Commander and Chief of General Staff of the Royal Armed Forces (FAR), the 9th meeting of the Moroccan-American Defense Advisory Committee is held on January 20-21 in Rabat.The US delegation, made up of several senior civilian and military officials of the US defense, is led by Ms. Amanda J. Dory, Deputy Assistant Secretary of Defense for African Affairs, accompanied by the United States Ambassador in Rabat, the FAR General Staff said in a statement.The US delegation was received, on Wednesday at the General Staff of the FAR, by General de Corps d’Armée Bouchaib Arroub, Inspector General of the FAR and Commander of the Southern Zone, the same source said.A plenary session was co-chaired by General de Corps d’Armée Bouchaib Arroub, Inspector General of the FAR and Commander of the Southern Zone Bouchaib Arroub and Amanda J. Dory, and attended by members of the US delegation and officials of FAR General Staff and Royal Gendarmerie. With MAP read more

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TimorLeste hospital receives lifesaving obstetrics equipment from UN

4 February 2010To help combat high maternal mortality rates in Timor-Leste, the United Nations Population Fund (UNFPA) has supplied equipment to assist in child delivery to a hospital in the capital of the fledgling nation. To help combat high maternal mortality rates in Timor-Leste, the United Nations Population Fund (UNFPA) has supplied equipment to assist in child delivery to a hospital in the capital of the fledgling nation.The equipment was handed over to the Department of Obstetrics and Gynecology of the Guido Valadares National Hospital on 28 January.Pornchai Suchitta, UNFPA Representative, voiced hope that the equipment will help to save lives.UNFPA has been working with the hospital since 2000 to build the capacity of the obstetrics and gynecology staff to tackle the high maternal mortality rate and other issues related to women’s health in the country.According to a joint study by UNFPA, the World Health Organization (WHO), the UN Children’s Fund (UNICEF) and the World Bank, nearly 200 women died in Timor-Leste in 2005 while or shortly after giving birth. read more

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Syria Security Council unites in support of RussiaTurkey efforts to end violence

The United Nations Security Council today unanimously adopted a resolution welcoming and supporting the efforts by Russia and Turkey to end violence in Syria and jumpstart a political process for the war-torn Middle Eastern country.Also in the Russian-drafted resolution, the 15-member Council “takes note of” the documents issued by Russia and Turkey about the agreements the two countries have brokered, including a nationwide ceasefire and a plan to convene political talks in Kazakhstan’s capital, Astana, between the Syrian Government and opposition groups, in January.The Council “looks forward to” the meeting in Astana, viewing it as “an important part of the Syrian-led political process” and “an important step ahead of the resumption of negotiations under the auspices of the United Nations in Geneva on 8 February 2017.”Further in the text, the Council stressed the importance of fully implementing all relevant Security Council resolutions, particularly 2254 (2015) and 2268 (2016), which endorsed an inclusive and Syrian-led political process based on the Geneva Communiqué of 30 June 2012 as the only sustainable solution to the current Syrian crisis, now in its sixth year.Secretary-General Ban Ki-moon welcomed the Council’s unanimous adoption today and efforts by Russia and Turkey to reduce violence and save civilian lives in Syria through the establishment of a ceasefire, his spokesman said in a statement.The Secretary-General also takes note of the resolution’s call for the full implementation of resolutions 2254 (2015) and 2268 (2016), and he urges all parties to heed the renewed call in the resolution for rapid, safe and unhindered humanitarian access throughout Syria, the spokesman said.“The Secretary-General hopes that these developments will lead to productive talks in Astana, Kazakhstan, and contribute to intra-Syrian negotiations to be convened by the United Nations in Geneva on 8 February 2017 and pursuant to resolution 2254,” the spokesman added.Under-Secretary-General for Humanitarian Affairs Stephen O’Brien joined Mr. Ban in welcoming today’s Council action.“As the people of Syria continue to suffer immeasurably, it is imperative that the political will demonstrated today translates into increased, sustained and impartial humanitarian access to the millions of people who have suffered far too long and are currently in the grips of a merciless cold winter without adequate shelter, protection and basic supplies,” said Mr. O’Brien, also the Emergency Relief Coordinator, in a statement. read more

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Edinburgh Fringe Joke about being fired from a Job Centre named funniest at

“A guy said he worked in the Jobcentre and I said the joke that has now won the award.”Because it got such a nice reaction on the night I thought I had to do something with it as a line.”I didn’t expect to be winning an award for what was essentially a brain fart!”Previous winners of the award include Tim Vine, Stewart Francis and Zoe Lyons. Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily  Front Page newsletter and new  audio briefings. A joke about being fired from a Job Centre was named the funniest at this year’s Edinburgh Festival Fringe.Adam Rowe won the 11th annual award for Dave’s Funniest Joke Of The Fringe with the line: “Working at the Jobcentre has to be a tense job – knowing that if you get fired, you still have to come in the next day.”The joke from Rowe’s show Undeniable won with 41 per cent of a public vote on a shortlist of gags picked by comedy critics.The former bartender began doing stand-up in 2010 and has previously been crowned Liverpool Comedian of the Year.On winning the award, Rowe said: “I thought my agent was lying. He rang me and told me I couldn’t tell anyone for a week which has been almost impossible.”I’m massively taken aback by it, I’ve never seen myself as being in the running for things like this.”It’s a massive honour and a genuinely huge surprise.” Explaining how he came up with the punchline, Rowe said: “I actually wrote it when I was on stage when I was hosting a gig in Liverpool.”It was a bit of crowd work that stayed with me. I was doing the usual compering thing, asking people what they do for a living. Maths student Ken Cheng won last year’s prize with the line: “I’m not a fan of the new pound coin, but then again, I hate all change.”The award, which was voted on by 2,000 people, lists jokes anonymously to avoid any bias towards well-known comedians. Dave channel director Luke Hales said: “This year, the news agenda and every day British idiosyncrasies have provided some wonderful opportunities for comedians to use their creative and comic genius in giving us all a giggle.”As ever, we have enjoyed some quite brilliant one-liners and are delighted to crown Adam Rowe as the recipient of this year’s Dave’s Funniest Joke of the Fringe Award.” read more

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The right to bear hair

first_imgThe orders are clear: no beards, moustaches, mutton chops, goatees or ponytails. You’d think those were the rules to enter an upmarket club or bar, but no, these are the new rules Victoria Police have adopted to make the force more presentable. They must have thought the new rule introduced in 2012 wouldn’t have tickled that many hairs, but now they find themselves preparing to defend their decision at the Victorian Supreme Court.Sixteen bearded officers, including Greek Australian detective Vasilios Chrisant, have joined forces to defend their right to sport a bit of facial hair. They say facial hair has nothing to do with work, and as community members they deserve to be able to express themselves as they wish.“For 37 years I have not disobeyed command, but this order has nothing to do with my work, it has to do with my personality and with my image,” he tells Neos Kosmos. “It is a matter of principle, so I decided, along with my other colleagues, that I claim the right to my appearance.”Sporting a well trimmed goatee, Sergeant Chrisant refused to part with his hair and was suspended for three months with pay on March 25. Currently, facial hair is allowed for medical, cultural or religious reasons.Sergeant Chrisant doesn’t believe that having exceptions to the rule makes for a valid argument.“This is what we cannot understand,” he says.“If the police administration wants to impose a specific look at all, do it without exception.”The bearded policemen initially lost an appeal to the rule when the Victorian Civil and Administrative Tribunal (VCAT) that found the ban was not discriminatory.But that has not stopped them from taking the matter further. At the moment, the matter is going to court thanks to the help of pro bono lawyers.“Because the case is important and the first of its kind in Victoria, our lawyers have undertaken it pro bono,” he says.If the case doesn’t go their way, Sergeant Chrisant says he will respect the ruling and say goodbye to his facial fashion.It’s not just the men of the force that have to comply to strict rules of appearance. Women in the force will also face disciplinary action if they wear make-up or nail polish that is not natural looking or in neutral tones.Victoria Police says an overwhelming majority of police were in favour of the new appearance code. Facebook Twitter: @NeosKosmos Instagramlast_img read more

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APS wins TASA interschool quiz competition

first_imgHyderabad: Telangana and Andhra Sub Area (TASA) Inter school quiz competition 2019-20 organised at 1 EME Centre, Secunderabad recently. Students from 09 schools including Kendriya Vidyalaya Golconda No.2, KV Tirumalagiri, Army Public School Bolarum, Sainik School Kalikiri, APS Golconda, KV Bolarum, KV Bowenpally, APS R K Puram and KV Picket were participated in the competition. Also Read – Students to rate performance of teachers Advertise With Us After five rounds of knowledge churning and excitement, Army Public School R K Puram declared the winners of the competition and APS Bolarum School stood in second place. The chief guest, Brigadier YS Kumar, HQ Telangana and Andhra Sub Area distributed prizes to the participants. Speaking on the occasion, Brigadier YS Kumar said that “the competition is an opportunity to boost general knowledge, understanding, presence of mind, develops critical thinking and creative skill which will help students to take appropriate decision to progress in life”.last_img read more

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Raghava Lawrence on redirecting Akshay Kumar starrer Laxmmi Bomb If given proper

first_imgAkshay Kumar with filmmaker Raghava Lawrence; Laxmmi Bomb movie posterTwitterAn upset director Raghava Lawrence had walked out of Akshay Kumar starrer Laxmmi Bomb after the first look of the Hindi remake of his blockbuster film Kanchana was released online without his knowledge by the Khiladi actor. The Tamil filmmaker had tweeted a few days ago that he was stepping down as the film’s director citing lack of respect from the film’s team. Now, Raghava has now hinted at donning the director’s hat again for the project.In a long note, Raghava said that he was equally upset for the past one week adding that he had waited for a very long time to direct the film and had spent a lot of time in pre-production. He said that the producers of Laxmmi Bomb will be coming to meet him in Chennai and he may once again take on the director’s seat if he is given proper respect for his job.Raghava Lawrence, who was supposed to direct Laxmmi Bomb, was not aware of the release of Akshay Kumar’s first look from the film and he learned it from of one of his friends. He had immediately decided to opt of the film.In his earlier statement, Raghava had said that there were more than one reason for him walking out of this project. He had said he would soon meet Akshay Kumar and submit the film’s script as a part of his professional ethics but he would not continue to be in this film.After Raghava’s move, it was reported that the makers of the film are on the lookout of a new director and it was being said that the producers had brought director Farhad Samsi to direct the film.In the film, Kiara Advani has been paired opposite Akshay and will be playing the role of his onscreen wife. Unlike the original Tamil film, Kiara’s role will be meatier and prove to be crucial in the exorcism sequence.Read the full unedited note of Raghava Lawrence on directing Laxmmi Bomb starring Akshay Kumar.”Hi friends and fans, I had tweeted about stepping out of the Hindi film ‘Laxmmi Bomb’ a few days back. Post my tweet both Akshay Kumar Sir fans and my fans have been requesting me to do this film. I’m over-whelmed with their genuine love. But trust me, I’m equally upset for the past 1 week as you are. I was very thrilled to do this film, as I almost waited very long to direct this film, spent a lot of quality time on pre-production works and have also blocked my dates for this film. Tomorrow, the Producers are coming to Chennai to meet me. It’s completely in their hands now, if I’m given proper self-respect for my job, then I’ll think about it. Let’s see after the meeting. Wanted to share this message to all the fans who were genuinely concerned. Love, Raghava Lawrence.”last_img read more

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Foreign artists Indian shores

first_imgIt’s raining foreign artists in the city and Delhiites seem to be lapping it all up. At Visual Arts Gallery, seven British artists are showing in a group show titled Critical Narratives in Colour and form, and each one of them reiterates the importance of ‘creating’ art with one’s own hand. In one of the mixed media paintings that Angus Pryor has created, he fills his canvas with motifs of bindus, swastikas, animal and birds — images that he has absorbed in Delhi. Pryor is also the curator of this show which is part of a two day workshop-cum-seminar organised by art curator Dr Alka Pande. Also Read – ‘Playing Jojo was emotionally exhausting’‘I have been travelling to India for many years now and I found that there is a strong similarity in our practice of storytelling through art,’ says Pryor. The exhibition that boasts of other British artists like Mavernie Cunningham, Jez Giddings, William Henry, Mark Howland, Chris Hunt and Aya Mouri, hence, places a deliberate emphasis on painting and print making which was and continues to be an essential part of Indian art practice.In another group show titled Whose History, Which Stories — presented by Shrine Empire at The Stainless — curator Oindrilla Maity Surai has put together evocative videos, paintings and installations by five South Korean and five Indian artists. According to Surai, ‘The exhibition tries to find out the many similarities and idiosyncrasies that prevail in these two neighbouring countries. It is a platform where two neighbouring countries  come together through art.’ Also Read – Leslie doing new comedy special with NetflixFor instance, SangHwa Park’s videos from the Inner Dream series portray the pessimism of the 21st century. Science and technology have not associated themselves with well being alone. Desire continues to pervade society. War is also the subject for YoungTae Kim and ChangWon Lee’s photographs. They question the validity of war, the freedom fighter and their memories.The artist to watch out for, however, is Gim Gwang Cheol whose videos of his intensely charged performances question the human situation in a sprawling city that grows oblivious of its past, its sacrifices to earn a free nation state and what it actually promised to achieve. Gwang Cheol writes about his project: ‘That Hitler’s face is placed inside Marilyn’s mouth is itself illusion. It is an attempt to express rejection toward unconditional worship of any icon. Uncontrolled desire for power and fame violates life so I reveal these elements through my art.’ At Vadehra Art Gallery, a solo show titled Passageway by German artist Wolfgang Laib is on view. His works are studies of form, colour and material explore natural material such as beeswax, pollen, rice and stone. In Lado Sarai, Exhibit 320 is showing photographs by three Singaporean artists along with three Indians — Sumit Dayal, Ankit Goyal, Akshay Mahajan, Nguan, Carrie Lam and Sean Lee — who explore the theme of self and identity through a visual medium.last_img read more

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Tata Steel workers march to save Scottish plants

first_imgTata Steel workers from two of the Indian steel giant’s Scottish plants set to be mothballed took out a march in an attempt to save them from closure. The workers, joined by councillors and Labour party members, are calling for action by the Scottish and UK governments to protect the steel industry and its jobs, days after Britain’s biggest steelmaker announced the lay-off under a restructuring deal. Up to 270 jobs could be lost under Tata Steel’s plans to mothball Dalzell and Clydebridge steel plants along with 900 posts at the firm’s facility in Scunthorpe. A total of 225 jobs are threatened at the Dalzell plate- rolling works in Motherwell, along with 45 posts at the Clydebridge plant in Cambuslang region of Scotland.  Also Read – Punjab & Sind Bank cuts MCLR by up to 20 basis pointsTata, along with a number of other steel companies operating in Europe, has blamed cheap Chinese imports and high energy costs for a collapse in steel prices. Community union representative Derek Fearon said: “We are trying to raise awareness of the campaign, and hopefully through this Tata will become a responsible seller.“The main aim of the taskforce, the priority of it, is for the two plants to remain open. The mood is upbeat, the guys are still positive that everything can be done for the two plants to be saved.”  The Scottish government has pledged to do everything possible to keep the plants operational, with its preferred option being to find a buyer.last_img read more

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White wine not necessarily with white meat ditto for red

first_imgConvnetional wisdom has it that while wine is to be paired with white meat and red wine with red wine. Correct? “Not so,” asserts sommlier Prateek Arora.“Pair a pork cooked with sage with a white wine and you get a blast of tastes,” Arora said at a Wine and Dine outing at the Mehrauli swish Qla fine diner here on Wednesday.He then went a step further.“Contrary to conventional wisdom, Indian foods and wine can be a great marriage but certain tweaks are required to the food, the melange of spices makes this possible,” Arora, a Qla director, who plays the guitar to unwind and who was named sommlier of the year at the recent delWine Excellance Awards, explained.  Also Read – Add new books to your shelfBut to begin at the beginning.“Welcome to the chemistry lab,” Arora proclaimed as the guests moved into the vast bar after a rather unusual, but refreshing welcome drink – sparkling wine with passion fruit puree and dehydrated pine apple – served in the courtyard of the 100-cover eatery, equally divided between the inside and the outside.“To truly appreciate wine, you have to first unlearn what you know. You’ve gotta see if the wine talks to you. So, smell, agitate the wine and then slip slowly. Wine is all about awakening your senses,” he explained. Also Read – Over 2 hours screen time daily will make your kids impulsive“Wine is like a little baby trapped in a bottle. The moment the bottle opens, you are bringing out its best. Look at it, swirl it and see what it does to your nose. Taste it and it tells you what it is all about on your palette. It’ll create perception areas on your tongue,” Arora elaborated. It was then time for the first of the pairings, a delicate gougers light pastry made with three different types of cheese and chilli flakes. What the white wine did was to enhance the flavours of the cheese and sharpen the impact of the chilli flakes. Quite a combination! It was then time to move into the kitchen where Chef Priyam Chatterjee, who was born into a family where feasts and thriving on culinary traditions were a daily deal, deftly cooked up an appetiser using shimiji mushrooms, butter, grated cheese and a variety of herbs with a generous portion of white wine.It was then time for the sit-down part of the evening over a vegetrian white sauce risotto and (vegetarian/non-vegetarian red sauce pasta – served in tandem with a white an a red wine).That proved quite a moment as the red wine, which went down smoothly when sipped independently, tasted a mite sweet when combined with the two dishes – proof of wine creating “perception areas” on the tongue.“I’m absolutely passionate about wine,” said Arora, who explained that he uses his wine palate to deconstruct and construct drinks to do justice to each ingredient which, according to him, should shine through in what a guest gets in the glass. For him, each of the parts is as important as the whole. And this is what prompted him to lauch Wine Evening at Qla once a month.“We choose the dates with care to ensure they don’t clash with anything important. We want our guests to spend a quiet evening and not get hassled about being caught in traffic or any other eventuality,” Arora concluded.last_img read more

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Brisk walk staves off disability

first_imgJust one hour a week of brisk walking may stave off disability in older adults with arthritis pain, aching or stiffness in a knee, hip, ankle or foot, according to a study unveiled on Monday. “This is less than 10 minutes a day for people to maintain their independence. It’s very doable,” said Dorothy Dunlop, a professor at Northwestern University in the US. “This minimum threshold may motivate inactive older adults to begin their path towards a physically active lifestyle with the wide range of health benefits promoted by physical activity,” said Dunlop, lead author of the study published in the American Journal of Preventive Medicine. Also Read – Add new books to your shelfAbout two in five people with osteoarthritis – most of whom have it in their lower joints – develop disability limitations, researchers said. The study found an hour of weekly moderate-to-vigorous physical activity allowed older adults to maintain their ability to perform daily tasks like getting dressed or cross a street before a traffic light walk signal changed. The weekly hour of exercise reduced their risk of mobility disability by 85 per cent and their risk of activities of daily living disability by almost 45 per cent. Also Read – Over 2 hours screen time daily will make your kids impulsiveFour years after the start of the study, 24 per cent of adults who did not get the weekly hour of brisk physical activity were walking too slowly to safely cross the street, and 23 per cent reported problems performing their morning routine. The researchers analysed four years of data from more than 1,500 adults in the national Osteoarthritis Initiative from Baltimore, Pittsburgh, Columbus and Pawtucket, Rhode Island. All the adults had pain, aching or stiffness in lower extremity joints from osteoarthritis but were free of disability when they began the study. Their physical activity was monitored using accelerometers. “Our goal was to see what kind of activity would help people remain free of disability,” Dunlop said. Guidelines in the US recommend older adults with arthritis should participate in low-impact activity. For substantial health benefits including reducing the risk for heart disease and many other chronic diseases, these guidelines recommend older adults participate in at least 2.5 hours a week of moderate-intensity activity. However, that level of activity can be daunting for inactive older adults with lower extremity pain, Dunlop said. “We hope this new public health finding will motivate an intermediate physical activity goal. One hour a week is a stepping stone for people who are currently inactive. People can start to work towards that,” Dunlop said.last_img read more

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The Browns should give up 5 picks for Jimmy Garoppolo if thats

first_imgLive from Super Bowl LI in Houston:Reports coming out of Cleveland say the Browns will look to make a trade to acquire Jimmy Garoppolo from the Patriots in the offseason. Colin has said on multiple occasions he thinks Jimmy G is the real deal. He thought he showed enough in his fill-in role for Tom Brady to prove that he’s as sure of a thing as there is this offseason.This year’s crop of college quarterbacks is thin, and none looks ready to play and win right away. Colin thinks the Browns need to do whatever it takes to get a deal done for Garoppolo, even if it means forking over half their draft picks to Bill Belichick. Having a bunch of draft picks is worthless if you don’t have a quarterback. It’s an easy call, only the Browns could screw it up.“Just get the quarterback. Garoppolo, you’ve seen enough. A helluva a lot more with Garoppolo than Mitch Trubisky. Go get him! 5 picks. You’ve got like 12 picks next year. Give half of them up, who cares? Get the quarterback right!”Charles Barkley responded to LeBron James’ public comments ripping him. Barkley said he’s not upset with James, but didn’t back off his criticism that the King was whiny for making comments ripping the Cavs front office, and complaining that the salary cap strapped Cavs need to add another player.Colin thinks NBA players are the most thin-skinned because the NBA is all about them. Compared to the cutthroat NFL where contracts aren’t guaranteed and endorsement money is sparse, NBA players have guaranteed money and endless streams of endorsements. The NFL is anti-player, and the NBA is run by the players. It’s why they get so bent out of shape when they get criticized.“In the NFL if you go on a boat for three hours with teammates, you are not a team player. You are a disruption. You should be traded. In the NBA, you can go on a boat with rivals. ‘It’s all good!! We’re just friends.”Guests:Howie Long – NFL Hall of Famer and co-host of Fox NFL Sunday is on look back on his Super Bowl memories as a player; why he’s so happy for his son Chris to play in a Super Bowl after years of playing on losing teams; and what moment made him realize he needed to appreciate how rare it was to get to a Super Bowl.Nate Burleson – Former NFL wide receiver and co-host of Good Morning Football on the NFL Network is on-set to explain why he doesn’t completely disagree with Colin’s take on diva wide receivers; why he is a self-described undercover diva; what Pete Carroll did to change the culture in Seattle; and Colin somehow remembers his dad’s jersey number from his playing days at the University of Washington in the 70’s.Eric Mangini – Former Browns and Jets head coach, and Patriots coordinator is on set to look back on his first Super Bowl as an assistant with New England; why he hired Dan Quinn as a defensive line coach during his time in New England; why it’s so crucial for teams to get their preparation done before they get to the Super Bowl; and why if Brady knows the coverage, it’s over.Trevor Siemian – Denver Broncos quarterback is on set to talk about sleeping upright in a chair after shoulder surgery; his scouting report on the Super Bowl teams after facing them; if Tony Romo to Denver rumors bother him; and how the Super Bowl experience has changed since he first experienced it as a player.Dan Reeves – Former Broncos and Falcons head coach is on set to look back at his Super Bowl experiences as a player and a coach; which loss stung the most; what impresses him most about Bill Belichick; how the Super Bowl experience is almost unrecognizable from his playing days.last_img read more

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Work in travel youre better off

first_imgThe travel trade has been revealed one of the most promising industries. Your coveted position within the travel industry affords you the ability to earn higher wages, have greater access to educational opportunities and enjoy better career progression, according to the results of a new study.For this one-of-a-kind study, the U.S. Bureau of Labor Statistics collected more than 30 years of longitudinal data, which was then analysed by Oxford Economics and the U.S. Travel Association. “The data is conclusive: workers whose first job is in the travel industry progress further in their careers than individuals who get their start in other industries, and travel industry work experience helps Americans earn higher wages and attain an education,” U.S. Travel Association president and chief executive Roger Dow said.“Travel jobs provide important, transferable skills that are indispensable to career success, and careers in travel deliver financial security with the majority of travel industry workers earning a middle-class income or higher.”The research, ‘Fast Forward: Travel Creates Opportunities and Launches Careers’ presented numerous case studies, which were summarised and then compared to individuals who began work in other industries.Key findings revealed the average maximum salary for employees who begin their career in the travel industry is significantly higher than those who started in other industries. The travel industry was also seen to promote educational opportunities and build rewarding careers. “In recent years, the travel industry has quietly emerged as one of America’s leading drivers of growth and job creation,” U.S. Travel Association senior vice president for research and economics David Huether said. “Every dollar spent on travel has a ripple effect benefitting other sectors of the economy… the travel industry injects US$1.9 trillion into the national economy and supports 14.4 million jobs.” Source = e-Travel Blackboard: P.Tlast_img read more

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Grace expects Greinke trade to have emotional impa

first_img Grace expects Greinke trade to have emotional impact For example, I asked King to bottom line Cards new head coach Bruce Arians. “Players will play for this guy,” King said slowly and emphatically. “X’s and O’s are very important. But there’s also the motivation of men. Bruce Arians is going to motivate these guys.” Speaking of team leaders, I put the following question to King: “If quarterback, head coach, and general manager are the lifeblood of any NFL organization, then how do you think the Cardinals will fare with Palmer, Arians, and Keim in the years to come?” “That’s a great question. In my opinion, if there was one quarterback out there this off-season, including the rookies, who this team could’ve acquired, I think it would’ve been Carson Palmer. Because Arians wants a QB who can throw the ball downfield. He wants a QB who’s a veteran, who’s been there before. And Carson Palmer really fits that,” King said. And when it comes to Palmer, King made sure to mention that acquiring Palmer via trade is not just a matter of answering “who” is playing QB, but “how”…as in, “how much?” Top Stories The 5: Takeaways from the Coyotes’ introduction of Alex Meruelo Former Cardinals kicker Phil Dawson retires “Let’s be honest, they paid nothing for Carson Palmer. And that’s a little baptism by fire for Steve Keim. That’s really his first big decision, when you think about it.“(Keim) won that one. He routed the Raiders on that one,” King continued. “Of course, the Raiders didn’t have a lot of choice because everybody knew they had to cut him, but Keim made a really good trade.” What sort of fit will Palmer prove to be? And what’s the upside? That was the final topic.“Carson Palmer, I think, has been bruised and battered by his experience in Oakland,” said King. “Carson Palmer has always wanted to throw the ball downfield. He’s always wanted a weapon like Larry Fitzgerald.” 0 Comments   Share   There are media members who cover events. And then there are media members who are billed as the event. And let’s just say there’s a reason that Peter King had his name on the Cardinals Pre-Pat’s Run charity event recently. As a longtime NFL insider for Sports Illustrated, Peter King writes. And people read. He churns out multi-media content and NFL fans consume on various platforms.But last Friday, I had a few minutes to pose a few questions — in person. After King eloquently responded to questions about Tillman and King’s longtime former hometown of Boston, we audibled into the Arizona Cardinals. Derrick Hall satisfied with D-backs’ buying and sellinglast_img read more

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New York NY – Reported by Elite Traveler the Pri

first_imgNew York, NY – Reported by Elite Traveler, the Private Jet Lifestyle MagazineThis month, fine jewelry label Tamsen Z opens the doors to its first flagship boutique on Manhattan’s Madison Avenue.The chic new retail space occupies an impressive 1,600 square feet over two floors, with interiors overseen by designer and founder Tamsen Ann Ziff. The Upper East Side location, at 783 Madison Avenue between 66th and 67th streets, places Tamsen Z in the company of some of the city’s most luxurious retailers.The store’s unique design makes it the perfect home for Tamsen Z’s stunning, one-of-a-kind pieces. The 18-foot ceiling is highlighted by grand Austrian crystal chandeliers, recreations of those found in the Metropolitan Opera House. The gems themselves are displayed in Maccasar ebony and claro walnut burl cases, set upon a custom carpet designed by Ziff herself.“We are elated to open our doors on Madison Avenue this fall,” said Ziff of the new outpost. “The goal is to create a unique and welcoming environment where clients and collectors can learn about the unusual gems and minerals in each piece.”www.tamsenz.comlast_img read more

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That would allow E

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but know that personal feelings should not drive national legislation. To compare hearing ability in former musicians to people who never played an instrument. 2015. who gave up being the president’s chief of staff to become mayor of Chicago, The Deputy President of the Senate,上海千花网Eve,” After the text exchange. St.” said Sandra Harding. read more

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